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1

The role of complement in CD4+ T cell homeostasis and effector functions

Kolev, Martin, Le Friec, Gaëlle, Kemper, Claudia

Journal:

Seminars in Immunology

Year:

2013

Language:

english

File:

PDF, 1.53 MB

english, 2013

2

Complement — tapping into new sites and effector systems

Kolev, Martin, Friec, Gaelle Le, Kemper, Claudia

Journal:

Nature Reviews Immunology

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

3

Alloreactive CD4+ and CD8+ T cells express the immunotolerant HLA-G molecule in mixed lymphocyte reactions: in vivo implications in transplanted patients

Solène Le Rond, Joël Le Maoult, Caroline Créput, Catherine Menier, Marina Deschamps, Gaëlle Le Friec, Laurence Amiot, Antoine Durrbach, Jean Dausset, Edgardo D. Carosella, Nathalie Rouas-Freiss

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 468 KB

english, 2004

4

DNAX accessory molecule-1 (CD226) promotes human hepatocellular carcinoma cell lysis by Vγ9Vδ2 T cells

Olivier Toutirais, Florian Cabillic, Gaëlle Le Friec, Samuel Salot, Pascal Loyer, Matthieu Le Gallo, Mireille Desille, Cécile Thomas de La Pintière, Pascale Daniel, Françoise Bouet, Véronique Catros

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 359 KB

english, 2009

5

DAP10 associates with Ly49 receptors but contributes minimally to their expression and function in vivo

Ilaria Tassi, Gaelle Le Friec, Susan Gilfillan, Toshiyuki Takai, Wayne M. Yokoyama, Marco Colonna

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 223 KB

english, 2009

6

Major histocompatibility complex abnormalities in non-Hodgkin lymphomas

Bernard Drénou, Gaelle Le Friec, Marc Bernard, Céline Pangault, Jean-Marc Grosset, Thierry Lamy, Renée Fauchet, Laurence Amiot

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 166 KB

english, 2002

7

Complement: coming full circle

Gaëlle Le Friec, Claudia Kemper

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

8

Erratum to: Complement: Coming Full Circle

Gaëlle Le Friec, Claudia Kemper

Journal:

Archivum Immunologiae et Therapiae Experimentalis

Year:

2010

File:

PDF, 81 KB

2010

9

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

Cardone, John, Le Friec, Gaelle, Vantourout, Pierre, Roberts, Andrew, Fuchs, Anja, Jackson, Ian, Suddason, Tesha, Lord, Graham, Atkinson, John P, Cope, Andrew

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 862 KB

english, 2010

10

CD46: Just a Notch up your common complement regulator

Gaelle Le Friec, Laurence Bugeon, Margaret Dallman, Claudia Kemper

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 73 KB

english, 2010

11

The complement regulator CD46 regulates unconventional gammadelta T cell responses

Gaelle Le Friec, Pierre Vantourout, John Cardone, Andrew Roberts, Adrian Hayday, Claudia Kemper

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 81 KB

english, 2010

12

CD46 favours immunoregulation by promoting the switch of Th1 cells into IL-10 producing Treg cells

John Cardone, Gaelle Le Friec, Anja Fuchs, John P. Atkinson, Andrew Cope, Claudia Kemper

Journal:

Molecular Immunology

Year:

2010

Language:

english

File:

PDF, 70 KB

english, 2010

13

HLA-G and lymphoproliferative disorders

Laurence Amiot, Gaëlle Le Friec, Yasmine Sebti, Bernard Drénou, Céline Pangault, Valérie Guilloux, Xavier Leleu, Marc Bernard, Thierry Facon, Renée Fauchet

Journal:

Seminars in Cancer Biology

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

14

Clinical relevance of soluble HLA class I molecules in Waldenstrom Macroglobulinemia

Anne-Sophie Moreau, Yasmine Sebti, Alain Duhamel, Aldo M. Roccaro, Valérie Coiteux, Thomas Gastinne, Gaëlle Le Friec, Nicholas Burwick, Laurence Amiot, Allen W. Ho, Stephanie Poulain, Bernadette Henna

Journal:

European Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 144 KB

english, 2008

15

The CD46-Jagged1 interaction is critical for human TH1 immunity

Le Friec, Gaëlle, Sheppard, Devon, Whiteman, Pat, Karsten, Christian M, Shamoun, Salley Al-Tilib, Laing, Adam, Bugeon, Laurence, Dallman, Margaret J, Melchionna, Teresa, Chillakuri, Chandramouli, Smit

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

16

Detection of HLA-G in serum and graft biopsy associated with fewer acute rejections following combined liver–kidney transplantation: possible implications for monitoring patients

Caroline Creput, Gaëlle Le Friec, Rajia Bahri, Laurence Amiot, Bernard Charpentier, Edgardo Carosella, Nathalie Rouas-Freiss, Antoine Durrbach

Journal:

Human Immunology

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

17

Soluble HLA-G molecules are increased in lymphoproliferative disorders

Yasmine Sebti, Gaëlle Le Friec, Céline Pangault, Frédéric Gros, Bernard Drénou, Valérie Guilloux, Marc Bernard, Thierry Lamy, Renée Fauchet, Laurence Amiot

Journal:

Human Immunology

Year:

2003

Language:

english

File:

PDF, 248 KB

english, 2003

18

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

Andrew Cope, Gaelle Le Friec, John Cardone, Claudia Kemper

Journal:

Trends in Immunology

Year:

2011

Language:

english

File:

PDF, 650 KB

english, 2011

19

CD46-mediated Treg induction requires intracellular CD46 processing by gamma-secretase

Gaëlle Le Friec

Journal:

Molecular Immunology

Year:

2009

Language:

english

File:

PDF, 75 KB

english, 2009

20

CD46: A molecular switch between effector and regulator T cell responses?

John Cardone, Gaëlle Le Friec, Claudia Kemper

Journal:

Molecular Immunology

Year:

2009

Language:

english

File:

PDF, 62 KB

english, 2009

21

Modulation of HLA-G antigens expression in myelomonocytic cells

Myriam Onno, Gaëlle Le Friec, Céline Pangault, Laurence Amiot, Valérie Guilloux, Bernard Drénou, Sylvie Caulet-Maugendre, Patrice André, Renée Fauchet

Journal:

Human Immunology

Year:

2000

Language:

english

File:

PDF, 479 KB

english, 2000

22

Soluble HLA-G inhibits human dendritic cell-triggered allogeneic T-cell proliferation without altering dendritic differentiation and maturation processes

Gaëlle Le Friec, Béatrice Laupèze, Olivier Fardel, Yasmine Sebti, Céline Pangault, Valérie Guilloux, Alain Beauplet, Renée Fauchet, Laurence Amiot

Journal:

Human Immunology

Year:

2003

Language:

english

File:

PDF, 356 KB

english, 2003

23

Identification of Jagged1 as a novel ligand for CD46: An interaction required for normal induction and regulation of human TH1 responses

Gaelle Le Friec, Devon Sheppard, Christian M. Karsten, Pat Whiteman, Salley Shamoun, Adam Laing, Simon N. Waddington, James M. McDonnell, Veronique Fremeaux-Bacchi, Lionel Couzi, Jörg Köhl, Alistair B

Journal:

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

24

The novel Jagged1/CD46 interaction: A prime target for immune modulation by viruses?

Devon Sheppard, Pat Whiteman, Gaelle Le Friec, Simon N. Waddington, Richard Smith, Teresa Melchionna, Claudia Kemper, James M. McDonnell, Penny A. Handford, Susan M. Lea

Journal:

Year:

2012

Language:

english

File:

PDF, 81 KB

english, 2012

25

A complement a day keeps the Fox(p3) away

Le Friec, Gaelle, Köhl, Jörg, Kemper, Claudia

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 604 KB

english, 2013

26

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

Liszewski, M. Kathryn, Kolev, Martin, Le Friec, Gaelle, Leung, Marilyn, Bertram, Paula G., Fara, Antonella F., Subias, Marta, Pickering, Matthew C., Drouet, Christian, Meri, Seppo, Arstila, T. Petteri

Journal:

Year:

2013

Language:

english

File:

PDF, 4.03 MB

english, 2013

27

Medical Diary for the ensuing Week.

Kolev, Martin, Le Friec, Gaëlle, Kemper, Claudia

Journal:

Year:

1900

Language:

english

File:

PDF, 188 KB

english, 1900

28

XIXe congrês de la sociêté internationale d'hématologie et XVIIe congrès société internationale ce transfusion sanguine

Kolev, Martin, Le Friec, Gaëlle, Kemper, Claudia

Journal:

Annales de l'Institut Pasteur / Immunologie

Year:

1981

Language:

french

File:

PDF, 73 KB

french, 1981

29

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination

Grey, Corinne, Barthès, Pauline, Chauveau-Le Friec, Gaëlle, Langa, Francina, Baudat, Frédéric, de Massy, Bernard, Lichten, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 1.04 MB

english, 2011

30

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

Kolev, Martin, Dimeloe, Sarah, Le Friec, Gaelle, Navarini, Alexander, Arbore, Giuseppina, Povoleri, Giovanni A., Fischer, Marco, Belle, Réka, Loeliger, Jordan, Develioglu, Leyla, Bantug, Glenn R., Wat

Journal:

Year:

2015

Language:

english

File:

PDF, 3.96 MB

english, 2015

31

The Inhibitory Receptor NKG2A Sustains Virus-Specific CD8+ T Cells in Response to a Lethal Poxvirus Infection

Rapaport, Aaron S., Schriewer, Jill, Gilfillan, Susan, Hembrador, Ed, Crump, Ryan, Plougastel, Beatrice F., Wang, Yaming, Le Friec, Gaelle, Gao, Jian, Cella, Marina, Pircher, Hanspeter, Yokoyama, Wayn

Journal:

Year:

2015

Language:

english

File:

PDF, 4.39 MB

english, 2015

32

Generation of a double KO mouse by simultaneous targeting of the neighboring genes Tmem176a and Tmem176b using CRISPR/Cas9: key steps from design to genotyping

Lemoine, Aurélie, Chauveau-Le Friec, Gaëlle, Langa, Francina, Louvet, Cédric

Journal:

Journal of Genetics and Genomics

Year:

2016

Language:

english

File:

PDF, 1.87 MB

english, 2016

33

Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

Freeley, Simon, Le Friec, Gaelle, Kolev, Martin, Niyonzima, Nathalie, Espevik, Terje, Mollnes, Tom Eirik, Lappegard, Knut, Woodruff, Trent M., Monk, Pete, Kemper, Claudia

Journal:

Year:

2016

Language:

english

File:

PDF, 53 KB

english, 2016

34

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Niyonzima, Nathalie, Freeley, Simon, Arbore, Giuseppina, Le Friec, Gaelle, Lappegård, Knut Tore, Mollnes, Tom Eirik, Kemper, Claudia, Espevik, Terje

Journal:

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

35

The “ins and outs” of complement-driven immune responses

Freeley, Simon, Kemper, Claudia, Le Friec, Gaëlle

Journal:

Immunological Reviews

Year:

2016

Language:

english

File:

PDF, 2.37 MB

english, 2016

36

C3a modulates IL-1 b secretion in human monocytes by regulating ATP ef fl ux and subsequent NLRP3 in fl ammasome activation

Asgari, Elham, Friec, Gaelle Le, Yamamoto, Hidekazu, Perucha, Esperanza, Sacks, Steven S, Cook, H Terence, Kemper, Claudia

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

37

Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus

Ellinghaus, Ursula, Cortini, Andrea, Pinder, Christopher L., Friec, Gaelle Le, Kemper, Claudia, Vyse, Timothy J.

Journal:

European Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

38

Auto-regulation of Th1 responses through carboxypeptidase M-generated C5a-desArg

West, Erin E., Freeley, Simon, Le Friec, Gaelle, Kolev, Martin, Niyonzima, Nathalie, Espevik, Terje, Mollnes, Tom Eirik, Lappegard, Knut, Woodruff, Trent M., Monk, Pete, Kemper, Claudia

Journal:

Molecular Immunology

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

39

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Niyonzima, Nathalie, Freeley, Simon, Arbore, Giuseppina, Le Friec, Gaelle, Lappegård, Knut Tore, Mollnes, Tom Eirik, Kemper, Claudia, Espevik, Terje

Journal:

Molecular Immunology

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

40

A novel critical role for CD46 in chromatin packaging and direct gene regulation

Singh, Parul, Kunz, Natalia, Le Friec, Gaelle, Kazemian, Majid, Lavender, Paul, Kemper, Claudia

Journal:

Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

41

A ‘sweet spot’ for CD46 function through direct regulation of glycolytic enzymes

Kunz, Natalia, Le Friec, Gaelle, Singh, Parul, Lavender, Paul, Kazemian, Majid, Hess, Christoph, Kemper, Claudia

Journal:

Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 47 KB

english, 2018

42

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

Arbore, Giuseppina, West, Erin E., Rahman, Jubayer, Le Friec, Gaelle, Niyonzima, Nathalie, Pirooznia, Mehdi, Tunc, Ilker, Pavlidis, Polychronis, Powell, Nicholas, Li, Yuesheng, Liu, Poching, Servais,

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.01 MB

english, 2018

43

Complement receptor CD46 is a key co-stimulator for optimal human CD8+ T cell effector function

Arbore, Giuseppina, Le Friec, Gaelle, West, Erin E., Niyonzima, Nathalie, Rahman, Jubayer, Pavlidis, Polychronis, Powell, Nicholas, Afzali, Behdad, Lavender, Paul, Lachmann, Helen J., Kemper, Claudia

Journal:

Molecular Immunology

Year:

2018

Language:

english

File:

PDF, 49 KB

english, 2018

44

Encyclopedia of Immunobiology || Inflammatory Products of the Complement Pathway

Le Friec, Gaëlle

Year:

2016

Language:

english

File:

PDF, 434 KB

english, 2016

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